pentobarbital will lessen the extent or effect of diazepam buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check. Potent or moderate CYP3A4 inducers may perhaps boost amount of diazepam elimination; thus, efficacy of diazepam might be lessened.pentobarbital will minimize the extent or effect of diltiazem by impacting